Chargers Vs 49ers Preview
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The San Francisco 49ers (3-0) will look to complete a perfect preseason and move to 7-1 in exhibition games under head coach Mike Singletary when they host the San Diego Chargers (1-2) on Thursday.  The 49ers have lost four straight meetings with the Chargers and eight of nine overall but find themselves as small favorites at -3.5 on the current NFL spreads.

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