San Francisco 49ers at San Diego Chargers, Qualcomm Stadium, San Diego, CA
Thursday, December 16, 2010, 8:20 pm EST, TV: NFL
Opening Line: Chargers -9
Current Line: Chargers -9
Opening Total: 44
Current Total: 44.5
Money Line: Chargers -385 / 49ers +325

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Chargers Vs 49ers Preview
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The San Francisco 49ers (3-0) will look to complete a perfect preseason and move to 7-1 in exhibition games under head coach Mike Singletary when they host the San Diego Chargers (1-2) on Thursday.  The 49ers have lost four straight meetings with the Chargers and eight of nine overall but find themselves as small favorites at -3.5 on the current NFL spreads.

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