The Chicago Cubs and Boston Red Sox are set to play the most anticipated series of interleague play’s opening weekend with the first game of a weekend series Friday night at Fenway Park

Chicago Cubs at Boston Red Sox

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The Toronto Blue Jays host the Boston Red Sox in the final game of a shortened two-game series after tallying an extra-innings victory last night at the Rogers Centre

Boston Red Sox at Toronto Blue Jays

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The Boston Red Sox aim to return to .500 in the first game of a two-game set against the Toronto Blue Jays at the Rogers Centre

Boston Red Sox at Toronto Blue Jays

The Boston Red Sox dominated the Toronto Blue Jays in their first series meeting

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The Minnesota Twins and Boston Red Sox meet for he fourth and final game of a four-game set on Monday night at Fenway Park

Minnesota Twins at Boston Red Sox

Boston has captured wins in nine of the last 10 meetings with Minnesota at Fenway Park

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The Boston Red Sox look to gain revenge from an opening series loss to the Minnesota Twins on Saturday afternoon at Fenway Park

Minnesota Twins at Boston Red Sox

The Boston Red Sox continue to struggle during the 2011 season

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The Boston Red Sox and Los Angeles Angels may be a little fatigued in playing the final game of their four-game series due to last night’s game running into the wee hours of the morning

Los Angeles Angels at Boston Red Sox

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The Boston Red Sox continue to own the Los Angeles Angels heading into the third game of a four-game set at Fenway Park.

Los Angeles Angels at Boston Red Sox

The Boston Red Sox have won all six meetings with the Los Angeles Angels this year

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Boston has won three straight road games since beginning the season with a seven-game road losing streak heading into its third game with Los Angeles Saturday night

Boston Red Sox at Los Angeles Angels

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