49ers vs Colts Preseason Betting Preview
The 49ers are 3 point road favorites today, only the second team this week to be listed as a road fav by the NFL football betting oddsmakers.
The poor preseason record of the Indianapolis Colts over the last decade has made oddsmakers take notice and downgrade them significantly from how they would perform in the same situation during the regular season.  That is the easy explanation for why the Colts are home underdogs at +3 on the NFL betting odds against the San Francisco 49ers on Sunday.

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