San Francisco Giants vs. Los Angeles Dodgers: MLB Betting Odds and Picks

The San Francisco Giants (23-13) and Los Angeles Dodgers (19-18) will continue a National League West series Saturday afternoon at Dodger Stadium, with the first pitch scheduled for 4:10 p.m. ET

San Francisco Giants vs. Los Angeles Dodgers

The Los Angeles Dodgers are 2-3 as home favorites of -125 to -150 this season

San Francisco has won the first two games of this series against Los Angeles, including a 3-1 victory as -127 road favorites Friday, while going UNDER the betting total in each of those affairs. The Giants will be playing without first baseman Brandon Belt for the next six weeks—suffering a broken left thumb last night—a major injury for the dlub due to ranking among NL leaders with nine home runs. San Francisco is 1-3 as road underdogs of +125 to +150 this season, with the UNDEr going 2-1-1 in that situation.

Giants starting pitcher Matt Cain (0-3, 4.35 ERA) comes off the disabled list after slicing his pitching hand a couple weeks ago, with the club dropping four of his five outings this season. The right-hander is 0-2 with a 5.25 ERA in four road games—surrendering five home runs in 24 combined frames. In 29 career starts versus the Dodgers, Cain has compiled a 5-11 record and 3.58 ERA, including a 2-3 mark and 3.00 ERA in 14 appearances at this ballpark.

Los Angeles has dropped three games in a row, with each of those affairs falling short of the betting total. Dodgers first baseman Adrian Gonzalez is 1 for 27 at the plate in his last seven games, but outfielder Yasiel Puig is batting .405 over a nine-game hitting streak. Puig is 3 for 8 with a home run and two doubles lifetime against Cain. Los Angeles is 2-3 as home favorites of -125 to -150 this season, with no clear edge in terms of the total (2-2-1 Over/Under).

Dodgers starting pitcher Zack Greinke (5-1, 2.35 ERA) is coming off a 4-0 road defeat to the Washington Nationals last time out, as he allowed two runs and five hits over three innings of work. The right-hander is 2-0 with a 2.37 ERA in three home appearances—issuing three walks and striking out 27 batters in 19 combined frames. In three lifetime efforts against the Giants, Greinke has tallied a 1-0 record and 3.12 ERA.