San Diego Padres vs. San Francisco Giants: MLB Betting Odds and Picks

The San Diego Padres (13-14) and San Francisco Giants (15-11) will continue their National League West series Tuesday night at AT&T Park, with the first pitch scheduled for 10:15 p.m. ET

San Diego Padres vs. San Francisco Giants

San Francisco Giants SP Matt Cain is hoping to tally his first win of the season Tuesday

San Diego has won back-to-back games, including a 6-4 victory over San Francisco as +156 road underdogs Monday night, while going OVER the betting total of 6.5. The Padres own a 7-4 record in their last 11 games against the Giants with a team batting average of .266 with 15 home runs and an average of 4.8 runs over that span. San Diego is 3-8 after a win this season,, with no clear edge in terms of the betting total (5-5-1 Over/Under).

Padres starting pitcher Eric Stults (1-2, 4.15 ERA) has led the club to three consecutive victories, but he didn’t earn a decision in a 4-3 road victory over the Washington Nationals last time out—allowing two runs and 10 hits over 5.1 innings of work. The left-hander is 0-2 with a 4.80 ERA in three road appearances this season, with opposing hitters batting .338 against him. In 18 lifetime appearances (16 starts) versus the Giants, Stults is 7-4 with a 4.97 ERA.

San Francisco had its four-game winning streak snapped last night, but it still owns a solid 8-5 record at this ballpark in 2014. The Giants have fashioned the lowest home bullpen ERA in the majors with a 0.65 figure entering the series opener Monday—giving up just a single run in its last 21 innings of work. Offensively, the club recorded two hits or fewer with runners in scoring position in each of the last 14 contests. San Francisco is 4-1 as home favorites of -150 to -175.

Giants starting pitcher Matt Cain (0-3, 4.35 ERA) has yet to taste victory this season, but he didn’t earn a decision in a 12-10 road win over the Colorado Rockies last time out, as he allowed seven runs and 10 hits over six frames. The right-hander has gone 8-14 with a 3.77 ERA in 44 career April games. In 32 lifetime games versus the Padres, Cain has put together a 7-12 record and 3.04 ERA.