New York Yankees vs. Chicago Cubs: MLB Betting Odds and Picks

The New York Yankees (23-20) and Chicago Cubs (15-27) will open up a MLB interleague series Tuesday night at Wrigley Field, with the first pitch scheduled for 8:05 p.m. ET

New York Yankees vs. Chicago Cubs

The New York Yankees are 12-4 in their last 16 games as favorites of -151 to -200

New York had its four-game winning streak snapped in the second game of a day-night doubleheader Sunday, as it suffered a 5-3 setback to the Pittsburgh Pirates as +115 home underdogs, while going UNDER the betting total for a fifth consecutive contest. This will be the third series at this venue between the Yankees and Cubs since the 1938 World Series. The franchise won the first two meetings against Chicago by a 5-0 combined margin in the Bronx on April 16. New York is 12-4 in its last 16 games as a favorite of -151 to -200.

Yankees starting pitcher Masahiro Tanaka (6-0, 2.17 ERA) has led the club to wins in his last six trips to the mound, including a 4-0 road victory over the New York Mets last time out, as he surrendered just four hits in going the distance. The right-hander is 4-0 with a 1.82 ERA in four road efforts—issuing just a single walk and striking out 30 batters in 29.2 combined frames. Tanaka earned a 3-0 home win over the Cubs last month.

Chicago has won back-to-back games, including a 4-2 victory over the Milwaukee Brewers as +111 home underdogs Sunday, while going UNDER the betting total in each of those affairs. The Cubs hit just .148 against the Yankees in their first series of the 2014 campaign—managing just a single extra-base hit. It’s important to point out that closer Hector Rondon is 5-for-5 in save opportunities, and boasts a 1.33 ERA. Chicago is 4-1 in its last five games as home underdogs.

Cubs starting pitcher Jason Hammel (4-2, 3.06 ERA) has watched the squad drop his last three efforts, as he was handed a 5-3 road loss to the St. Louis Cardinals in his last outing—allowing five runs and five hits over 5.1 innings of work. The right-hander is 2-0 with a 3.15 ERA in three home appearances, with opposing hitters batting just .200 against him. In 18 lifetime appearances (12 starts) versus the Yankees, Hammel is 3-4 with a 5.04 ERA.