MLB Predictions: San Francisco Giants vs. Colorado Rockies

The San Francisco Giants (28-18) and Colorado Rockies (26-20) will continue a National League West series Wednesday night at Coors Field, with the first pitch scheduled for 8:40 p.m. ET

San Francisco Giants vs. Colorado Rockies

San Francisco Giants SP Matt Cain is 6-3 with a 4.60 ERA in 14 starts in the Mile High City

San Francisco has dropped three of its last four games, including a 5-4 setback to Colorado as a -113 road favorite Tuesday, while going UNDER the betting total for a third consecutive affair. Giants third baseman Pablo Sandoval has been leading the offense recently, but he went 0-for-4 last night after hitting .389 during his previous nine-game hit streak. It’s important to mention that catcher Buster Posey may be out of the lineup due to nerve irritation in his lower back. San Francisco is 25-8 in its last 33 games following a loss.

Giants starting pitcher Matt Cain (1-3, 3.92 ERA) has watched the club alternate wins and losses in his last four trips to the mound, as he comes off a 6-4 home victory over the Miami Marlins last time out. The right-hander is 0-2 with a 4.34 ERA in five road appearances—serving up five home runs in 29 combined frames. In 33 career starts versus the Rockies, Cain has put together a 17-8 record and 3.35 ERA, including a 6-3 mark and 4.60 ERA in 14 appearances at this ballpark.

Colorado has won back-to-back games, while the UNDER is 5-1 in its last six contests. The Rockies have put together a 16-6 home record in the early going this season, while they’ve also captured 10 of their last 13 games against the Giants at this ballpark. Outfielder Carlos Gonzalez may receive a day off, considering he’s gone 4 for 44 with 17 strikeouts versus Cain in his career. Colorado is 6-2 in its last eight games versus division rivals.

Rockies starting pitcher Jhoulys Chacin (0-2, 4.76 ERA) is still searching for his first win of the year, as he comes off a 3-2 loss on the road to the Kansas City Royals—allowing three runs and seven hits over six innings of work. The right-hander has put together a 22-21 record and 4.22 ERA in 64 career appearances at this venue, including a 3-3 mark and 4.38 ERA in his last six trips to the mound in that situation. Chacin is 5-5 with a 3.38 ERA in 15 outings against the Giants in his career.