Cleveland Indians vs. Los Angeles Angels: MLB Betting Odds and Picks

The Cleveland Indians (11-14) and Los Angeles Angels (11-13) will open up an American League series Monday night at Angel Stadium, with the first pitch scheduled for 10:05 p.m. ET

Cleveland Indians vs. Los Angeles Angels

The Los Angeles Angels return home after a 4-5 road trip

Cleveland suffered a three-game sweep against the San Francisco Giants over the weekend, including a 4-1 setback as -115 road favorites Sunday, while going UNDER the betting total for the third time in four contests. The Indians hit .162 overall and .100 with runners in scoring position over the course of the series—leading to just five total runs scored. Cleveland is 21-40 as road underdogs of +100 to +125 the last two-plus seasons, with the OVER going 32-26 in that situation.

Indians starting pitcher Justin Masterson (0-0, 4.50 ERA) has watched the club alternated wins and losses over his first five outings of the season, as he comes off a no decision effort in a 5-3 home victory over the Kansas City Royals last time out. The right-hander is allowing opponents to hit just .227 against him away from Progressive Field—issuing six walks and striking out 11 batters in 11.2 combined innings. In 12 career appearances (nine starts) versus the Angels, Masterson has compiled a 4-0 record and 2.45 ERA.

Los Angeles returns home after going 4-5 on its nine-game road trip, which ended with a 3-2 defeat to the New York Yankees as +145 underdogs on ESPN’s Sunday Night Baseball. The Angels have dropped seven of nine games that have been decided by a single run in the early going during the 2014 MLB campaign. The club went 2-4 versus Cleveland a year ago—getting swept when the teams met in Southern California. Los Angeles is 18-18 at home with a money line of -100 to -125 the last two-plus seasons.

Angels starting pitcher Tyler Skaggs (2-0, 3.21 ERA) has led the squad to wins in all four of his efforts, including a 7-2 road victory over the Washington Nationals last week, as he surrendered two runs and three hits over seven innings of work. The left-hander has yet to earn a decision at this venue—posting a 5.54 ERA in 13 combined frames. Skaggs will be facing the Tribe for the first time in his career.