NFL Week 4 Picks: Philadelphia Eagles vs. San Francisco 49ers

Philadelphia Eagles vs. San Francisco 49ers
Sunday, 9/28/14, 4:25 PM EST
Opening Point Spread: San Francisco -3.5
Current Betting Line: San Francisco -4
Opening Total: 51
Current Total: 49
Odds Courtesy of Bookmaker

The San Francisco 49ers need to run the football in Week 4

Philadelphia is 3-0 SU and 2-1 ATS through three games, as it comes off a 37-34 win over the Washington Redskins as four-point home favorites last week, while going OVER the betting total for a third consecutive contest. The Eagles have become the first squad in league history to win its first three affairs despite trailing by at least 10 points in each, which is important to consider when making your NFL betting picks. Philadelphia is 2-5 SU and 3-4 ATS as underdogs of 3.5 to 9.5 points the last two-plus seasons.

The Eagles racked up 379 yards of offense last week, which can’t be ignored when looking over the NFL betting odds, which has played a role in the team ranking second in the league in averaging 33.7 points per game. Philadelphia quarterback Nick Foles will lead that particular group in this game at Levi’s Stadium, as he owns a 127.8 passer rating over his last seven road games with 21 touchdowns and just two interceptions.

San Francisco is 1-2 SUATS and will look to avoid its worst start since dropping its first five affairs of the 2010 campaign. The 49ers really put things together at this point of the season a year ago under head coach Jim Harbaugh, as they won 11 of their final 13 games en route to another NFC championship game appearance. San Francisco is 4-3 SUATS as home favorites of 3.5 to 7 points since 2012, with the OVER going 4-3 in that situation.

The 49ers need to get back to pounding the football, which will provide balance to the offense and open things up for quarterback Colin Kaepernick. San Francisco has had its running backs carry the ball just 27 times the last two weeks—something that must change after tallying 116 yards in a season-opening victory over the Dallas Cowboys. The franchise owns a 17-12-1 SU all-time lead in this series, and earned a 24-23 road victory in the last meeting on Oct. 2, 2011.